Advanced information on the Nobel Prize in Chemistry 2002

نویسندگان

  • John B. Fenn
  • Koichi Tanaka
چکیده

The Nobel Prize in Chemistry for 2002 is to be shared between scientists working on two very important methods of chemical analysis applied to biological macromolecules: mass spectrometry (MS) and nuclear magnetic resonance (NMR). Laureates John B. Fenn, Koichi Tanaka (MS) and Kurt Wüthrich (NMR) have pioneered the successful application of their techniques to biological macromolecules. Biological macromolecules are the main actors in the makeup of life whether expressed in prospering diversity or in threatening disease. To understand biology and medicine at molecular level where the identity, functional characteristics, structural architecture and specific interactions of biomolecules are the basis of life, we need to visualize the activity and interplay of large macromolecules such as proteins. To study, or analyse, the protein molecules, principles for their separation and determination of their individual characteristics had to be developed. Two of the most important chemical techniques used today for the analysis of biomolecules are mass spectrometry (MS) and nuclear magnetic resonance (NMR), the subjects of this year’s Nobel Prize award.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Richard Willstätter and the 1915 Nobel Prize in chemistry.

One hundred years after his Nobel Prize, Richard Willstätter's achievements and the fascinating role he played in 20th century chemistry are discussed in this Essay. Several of his discoveries, such as the anthocyanidins, cyclooctatetraene, the ortho-quinones, and the structure of cocaine, will forever be associated with his name.

متن کامل

Pulsed Nuclear Magnetic Resonance

What we call “nuclear magnetic resonance” (NMR) was developed simultaneously but independently by Edward Purcell and Felix Bloch in 1946. The experimental method and theoretical interpretation they developed is now called “continuous-wave NMR” (CWNMR). A different experimental technique, called “pulsed NMR” (PNMR), was introduced in 1950 by Erwin Hahn. Pulsed NMR is used in magnetic resonance i...

متن کامل

The 2014 Nobel Prize in Chemistry: A Large-Scale Prize for Achievements on the Nanoscale

The 2014 Nobel Prize in Chemistry awarded to Eric Betzig, Stefan W. Hell, and William E. Moerner "for the development of superresolved fluorescence microscopy" can be seen as a combined prize for single-molecule detection and superresolution imaging. Neurons, arguably the most morphologically complex cell type, are the subject of choice for this application, now generically called "nanoscopy."

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2002